MGP Database

MGP000460

Ontology/Pathway Information

Entrez Gene ID942
Gene NameCD86 molecule
Gene Symbol CD86
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0009897 IEA:EnsemblCexternal side of plasma membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IC:UniProtKBCintegral component of membrane
GO:0043231 IEA:EnsemblCintracellular membrane-bounded organelle
GO:0005886 TAS:ReactomeCplasma membrane
GO:0015026 NAS:UniProtKBFcoreceptor activity
GO:0004872 TAS:ProtIncFreceptor activity
GO:0007568 IEA:EnsemblPaging
GO:0042113 IEA:EnsemblPB cell activation
GO:0007267 IC:UniProtKBPcell-cell signaling
GO:0071345 IEA:EnsemblPcellular response to cytokine stimulus
GO:0071222 IEA:EnsemblPcellular response to lipopolysaccharide
GO:0071248 IEA:EnsemblPcellular response to metal ion
GO:0051607 IEA:EnsemblPdefense response to virus
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0006955 TAS:ProtIncPimmune response
GO:0045087 TAS:ReactomePinnate immune response
GO:0043011 IEA:EnsemblPmyeloid dendritic cell differentiation
GO:0002668 IEA:EnsemblPnegative regulation of T cell anergy
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0048015 TAS:ReactomePphosphatidylinositol-mediated signaling
GO:0042104 IEA:EnsemblPpositive regulation of activated T cell proliferation
GO:0008284 TAS:ProtIncPpositive regulation of cell proliferation
GO:0045086 NAS:UniProtKBPpositive regulation of interleukin-2 biosynthetic process
GO:0045404 NAS:UniProtKBPpositive regulation of interleukin-4 biosynthetic process
GO:0043017 NAS:UniProtKBPpositive regulation of lymphotoxin A biosynthetic process
GO:0045630 NAS:UniProtKBPpositive regulation of T-helper 2 cell differentiation
GO:0045893 NAS:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0042493 IEA:EnsemblPresponse to drug
GO:0034341 IEA:EnsemblPresponse to interferon-gamma
GO:0001878 IEA:EnsemblPresponse to yeast
GO:0042110 IC:UniProtKBPT cell activation
GO:0031295 TAS:ReactomePT cell costimulation
GO:0002309 IEA:EnsemblPT cell proliferation involved in immune response
GO:0002224 IEA:EnsemblPtoll-like receptor signaling pathway
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_19183CD28 co-stimulation
REACT_19358CD28 dependent PI3K/Akt signaling
REACT_19238CD28 dependent Vav1 pathway
REACT_147727Constitutive PI3K/AKT Signaling in Cancer
REACT_19344Costimulation by the CD28 family
REACT_19405CTLA4 inhibitory signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_116125Disease
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_12578GAB1 signalosome
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_12464PI3K/AKT activation
REACT_147723PI3K/AKT Signaling in Cancer
REACT_21270PI-3K cascade
REACT_116008PI3K events in ERBB2 signaling
REACT_115961PI3K events in ERBB4 signaling
REACT_75829PIP3 activates AKT signaling
REACT_163769Role of LAT2/NTAL/LAB on calcium mobilization
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_115596Signaling by ERBB4
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_111040Signaling by SCF-KIT
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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