MGP Database

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MGP000516

Ontology/Pathway Information

Entrez Gene ID1031
Gene Namecyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Gene Symbol CDKN2C
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:BHF-UCLCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005634 IDA:BHF-UCLCnucleus
GO:0004861 IDA:BHF-UCLFcyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0007050 IDA:BHF-UCLPcell cycle arrest
GO:0000082 IDA:BHF-UCLPG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0030308 IDA:BHF-UCLPnegative regulation of cell growth
GO:0008285 IDA:BHF-UCLPnegative regulation of cell proliferation
GO:0042326 IDA:BHF-UCLPnegative regulation of phosphorylation
GO:0071901 IDA:GOCPnegative regulation of protein serine/threonine kinase activity
GO:0048709 IEA:EnsemblPoligodendrocyte differentiation
GO:0000079 IDA:BHF-UCLPregulation of cyclin-dependent protein serine/threonine kinase activity
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_821Cyclin D associated events in G1
REACT_1590G1 Phase
REACT_21267Mitotic G1-G1/S phases
REACT_169325Oncogene Induced Senescence
REACT_169436Oxidative Stress Induced Senescence
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
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