MGP Database

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MGP000557

Ontology/Pathway Information

Entrez Gene ID1138
Gene Namecholinergic receptor, nicotinic, alpha 5 (neuronal)
Gene Symbol CHRNA5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005892 IC:UniProtKBCacetylcholine-gated channel complex
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0004889 NAS:UniProtKBFacetylcholine-activated cation-selective channel activity
GO:0015464 IDA:UniProtKBFacetylcholine receptor activity
GO:0015276 TAS:DFLATFligand-gated ion channel activity
GO:0035095 IMP:UniProtKBPbehavioral response to nicotine
GO:0098655 NAS:GOCPcation transmembrane transport
GO:0006812 NAS:GOCPcation transport
GO:0034220 TAS:GOCPion transmembrane transport
GO:0007165 NAS:UniProtKBPsignal transduction
GO:0007268 TAS:UniProtKBPsynaptic transmission
GO:0006810 NAS:ProtIncPtransport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15461Acetylcholine Binding And Downstream Events
REACT_22126Activation of Nicotinic Acetylcholine Receptors
REACT_22352Highly calcium permeable nicotinic acetylcholine receptors
REACT_22303Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_22149Postsynaptic nicotinic acetylcholine receptors
REACT_22336Presynaptic nicotinic acetylcholine receptors
REACT_13477Transmission across Chemical Synapses
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