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MGP000602

UniProt Annotations

Entry Information
Gene Namechemokine (C-C motif) receptor 7
Protein EntryCCR7_HUMAN
UniProt IDP32248
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
InductionBy Epstein-Barr virus (EBV).
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Web ResourceName=Wikipedia; Note=CC chemokine receptors entry; URL="http://en.wikipedia.org/wiki/CC_chemokine_receptors";
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