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MGP000688

Record overview

MGPD IDMGP000688
Gene ID1401
SpeciesHomo sapiens (Human)
Gene NameC-reactive protein, pentraxin-related
Gene Symbol CRP
SynonymsPTX1;
Alternate namesC-reactive protein; pentraxin 1;
Chromosome1
Map Location1q23.2
SummaryThe protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
OrthologsView orthologs and multiple alignments for CRP

Proteins

C-reactive protein precursor
Refseq ID:NP_000558
Protein GI:55770842
UniProt ID:P02741
mRNA ID:NM_000567
Length:224
RefSeq Status:
MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEI
LFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSP
NVLNWRALKYEVQGEVFTKPQLWP
 
sig_peptide: 1..18
calculated_mol_wt: 2009
peptide sequence: 
MEKLLCFLVLTSLSHAFG

mat_peptide: 19..224
product: C-reactive protein
calculated_mol_wt: 23047
peptide sequence: 
QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSW
ESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFT
KPQLWP
 
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