MGP Database

MGP000688

Ontology/Pathway Information

Entrez Gene ID	1401
Gene Name	C-reactive protein, pentraxin-related
Gene Symbol	CRP
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005576	NAS:UniProtKB	C	extracellular region
GO:0005615	IDA:BHF-UCL	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0030175	IEA:Ensembl	C	filopodium
GO:0030426	IEA:Ensembl	C	growth cone
GO:0005509	IDA:BHF-UCL	F	calcium ion binding
GO:0015485	IEA:Ensembl	F	cholesterol binding
GO:0033265	TAS:BHF-UCL	F	choline binding
GO:0001849	IDA:BHF-UCL	F	complement component C1q binding
GO:0030169	IDA:BHF-UCL	F	low-density lipoprotein particle binding
GO:0006953	TAS:BHF-UCL	P	acute-phase response
GO:0007568	IEA:Ensembl	P	aging
GO:0071277	IEA:Ensembl	P	cellular response to calcium ion
GO:0006958	IEA:Ensembl	P	complement activation, classical pathway
GO:0050830	TAS:BHF-UCL	P	defense response to Gram-positive bacterium
GO:0006954	TAS:ProtInc	P	inflammatory response
GO:0010888	IDA:BHF-UCL	P	negative regulation of lipid storage
GO:0010745	IDA:BHF-UCL	P	negative regulation of macrophage derived foam cell differentiation
GO:0008228	TAS:BHF-UCL	P	opsonization
GO:1900006	IEA:Ensembl	P	positive regulation of dendrite development
GO:0051258	IEA:Ensembl	P	protein polymerization
GO:2000482	IDA:UniProtKB	P	regulation of interleukin-8 secretion
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0010288	IEA:Ensembl	P	response to lead ion
GO:0042060	IEA:Ensembl	P	wound healing

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_7956	Classical antibody-mediated complement activation
REACT_6932	Complement cascade
REACT_8012	Creation of C4 and C2 activators
REACT_6900	Immune System
REACT_8024	Initial triggering of complement
REACT_6802	Innate Immune System