MGP Database

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MGP000694

Ontology/Pathway Information

Entrez Gene ID1437
Gene Namecolony stimulating factor 2 (granulocyte-macrophage)
Gene Symbol CSF2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IEA:UniProtKB-KWCextracellular space
GO:0005129 TAS:ProtIncFgranulocyte macrophage colony-stimulating factor receptor binding
GO:0071222 IEA:EnsemblPcellular response to lipopolysaccharide
GO:0097028 IDA:DFLATPdendritic cell differentiation
GO:0001892 IEA:EnsemblPembryonic placenta development
GO:0042045 IEA:EnsemblPepithelial fluid transport
GO:0006955 IEA:InterProPimmune response
GO:0042116 IEA:EnsemblPmacrophage activation
GO:0043011 IEA:EnsemblPmyeloid dendritic cell differentiation
GO:0045918 IDA:BHF-UCLPnegative regulation of cytolysis
GO:2001240 IDA:BHF-UCLPnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:0045740 IDA:BHF-UCLPpositive regulation of DNA replication
GO:0010628 IDA:BHF-UCLPpositive regulation of gene expression
GO:0032747 IDA:BHF-UCLPpositive regulation of interleukin-23 production
GO:0010744 IDA:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0071803 IDA:BHF-UCLPpositive regulation of podosome assembly
GO:0042523 IDA:BHF-UCLPpositive regulation of tyrosine phosphorylation of Stat5 protein
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19184GPCR downstream signaling
REACT_19388G-protein beta:gamma signalling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_6900Immune System
REACT_27283Interleukin-2 signaling
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_23891Interleukin receptor SHC signaling
REACT_798Platelet activation, signaling and aggregation
REACT_14797Signaling by GPCR
REACT_22232Signaling by Interleukins
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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