MGP Database

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MGP000726

Ontology/Pathway Information

Entrez Gene ID1508
Gene Namecathepsin B
Gene Symbol CTSB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0036021 TAS:ReactomeCendolysosome lumen
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005622 TAS:ProtIncCintracellular
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005764 IDA:UniProtKBClysosome
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005730 IDA:HPACnucleolus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005518 IDA:BHF-UCLFcollagen binding
GO:0004197 IDA:BHF-UCLFcysteine-type endopeptidase activity
GO:0008234 IDA:UniProtKBFcysteine-type peptidase activity
GO:0008233 IDA:BHF-UCLFpeptidase activity
GO:0043394 IPI:BHF-UCLFproteoglycan binding
GO:0097067 IEP:UniProtKBPcellular response to thyroid hormone stimulus
GO:0030574 IDA:BHF-UCLPcollagen catabolic process
GO:0046697 IEA:EnsemblPdecidualization
GO:0030855 IEP:UniProtKBPepithelial cell differentiation
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0045087 TAS:ReactomePinnate immune response
GO:0006508 IDA:UniProtKBPproteolysis
GO:0051603 IDA:BHF-UCLPproteolysis involved in cellular protein catabolic process
GO:0042981 TAS:UniProtKBPregulation of apoptotic process
GO:0050790 IEA:InterProPregulation of catalytic activity
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_150401Collagen degradation
REACT_120729Collagen formation
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_121399MHC class II antigen presentation
REACT_6966Toll-Like Receptors Cascades
REACT_118632Trafficking and processing of endosomal TLR
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