MGP Database

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MGP000834

Ontology/Pathway Information

Entrez Gene ID1734
Gene Namedeiodinase, iodothyronine, type II
Gene Symbol DIO2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IC:UniProtKBCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0008430 IC:UniProtKBFselenium binding
GO:0004800 IDA:UniProtKBFthyroxine 5'-deiodinase activity
GO:0031625 IPI:UniProtKBFubiquitin protein ligase binding
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0042446 IEA:UniProtKB-KWPhormone biosynthetic process
GO:0001514 NAS:UniProtKBPselenocysteine incorporation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006590 TAS:UniProtKBPthyroid hormone generation
GO:0042403 IDA:UniProtKBPthyroid hormone metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15513Amine-derived hormones
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_15297Regulation of thyroid hormone activity
REACT_15292Thyroxine biosynthesis
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