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MGP000871

Record overview

MGPD IDMGP000871
Gene ID1812
SpeciesHomo sapiens (Human)
Gene Namedopamine receptor D1
Gene Symbol DRD1
SynonymsDADR; DRD1A;
Alternate namesD(1A) dopamine receptor; dopamine D1 receptor;
Chromosome5
Map Location5q35.1
SummaryThis gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DRD1

Proteins

D(1A) dopamine receptor
Refseq ID:NP_000785
Protein GI:4503383
UniProt ID:P21728
mRNA ID:NM_000794
Length:446
RefSeq Status:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWV
AFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSV
ISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSED
LKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
 
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