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MGP000902

Record overview

MGPD IDMGP000902
Gene ID1892
SpeciesHomo sapiens (Human)
Gene Nameenoyl CoA hydratase, short chain, 1, mitochondrial
Gene Symbol ECHS1
SynonymsSCEH;
Alternate namesenoyl-CoA hydratase, mitochondrial; enoyl Coenzyme A hydratase, short chain, 1, mitochondrial; enoyl-CoA hydratase 1; short-chain enoyl-CoA hydratase;
Chromosome10
Map Location10q26.2-q26.3
EC Number4.2.1.17
SummaryThe protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ECHS1

Proteins

enoyl-CoA hydratase, mitochondrial
Refseq ID:NP_004083
Protein GI:194097323
UniProt ID:P30084
mRNA ID:NM_004092
Length:290
RefSeq Status:
MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADI
KEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISA
QDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
 
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