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MGP000981

Record overview

MGPD IDMGP000981
Gene ID2069
SpeciesHomo sapiens (Human)
Gene Nameepiregulin
Gene Symbol EREG
SynonymsER;
Alternate namesproepiregulin;
Chromosome4
Map Location4q13.3
SummaryEpiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for EREG

Proteins

proepiregulin preproprotein
Refseq ID:NP_001423
Protein GI:4557567
UniProt ID:O14944
mRNA ID:NM_001432
Length:169
RefSeq Status:
MTAGRRMEMLCAGRVPALLLCLGFHLLQAVLSTTVIPSCIPGESSDNCTALVQTEDNPRVAQVSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTG
VRCEHFFLTVHQPLSKEYVALTVILIILFLITVVGSTYYFCRWYRNRKSKEPKKEYERVTSGDPELPQV
 
sig_peptide: 1..29
calculated_mol_wt: 3173
peptide sequence: 
MTAGRRMEMLCAGRVPALLLCLGFHLLQA

mat_peptide: 63..108
product: epiregulin
calculated_mol_wt: 5275
peptide sequence: 
VSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFL
 
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