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MGP001005

Record overview

MGPD IDMGP001005
Gene ID2149
SpeciesHomo sapiens (Human)
Gene Namecoagulation factor II (thrombin) receptor
Gene Symbol F2R
SynonymsTR; HTR; CF2R; PAR1; PAR-1;
Alternate namesproteinase-activated receptor 1; protease-activated receptor 1;
Chromosome5
Map Location5q13
SummaryCoagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for F2R

Proteins

proteinase-activated receptor 1 precursor
Refseq ID:NP_001983
Protein GI:166362740
UniProt ID:P25116
mRNA ID:NM_001992
Length:425
RefSeq Status:
MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSW
LTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDR
FLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS
AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSS
GQLMASKMDTCSSNLNNSIYKKLLT
 
sig_peptide: 1..21
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2218
peptide sequence: 
MGPRRLLLVAACFSLCGPLLS
 
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