MGP Database

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MGP001008

Ontology/Pathway Information

Entrez Gene ID2152
Gene Namecoagulation factor III (thromboplastin, tissue factor)
Gene Symbol F3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0031012 IDA:BHF-UCLCextracellular matrix
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IBA:GO_CentralCintegral component of membrane
GO:0031233 IC:BHF-UCLCintrinsic component of external side of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004896 IBA:GO_CentralFcytokine receptor activity
GO:0005543 IDA:BHF-UCLFphospholipid binding
GO:0002020 IPI:BHF-UCLFprotease binding
GO:0002543 IC:BHF-UCLPactivation of blood coagulation via clotting cascade
GO:0006919 IDA:BHF-UCLPactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0002541 IDA:BHF-UCLPactivation of plasma proteins involved in acute inflammatory response
GO:0007596 TAS:ReactomePblood coagulation
GO:0007598 TAS:ReactomePblood coagulation, extrinsic pathway
GO:0019221 IBA:GO_CentralPcytokine-mediated signaling pathway
GO:0045766 IDA:BHF-UCLPpositive regulation of angiogenesis
GO:0030335 TAS:BHF-UCLPpositive regulation of cell migration
GO:0001938 IDA:BHF-UCLPpositive regulation of endothelial cell proliferation
GO:0010641 IDA:BHF-UCLPpositive regulation of platelet-derived growth factor receptor signaling pathway
GO:0050927 IC:BHF-UCLPpositive regulation of positive chemotaxis
GO:0051897 IMP:BHF-UCLPpositive regulation of protein kinase B signaling
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1573Extrinsic Pathway
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_604Hemostasis
SMP Pathway Links
SMP IDDescription
SMP00269Acenocoumarol Action Pathway
SMP00280Alteplase Action Pathway
SMP00286Aminocaproic Acid Action Pathway
SMP00281Anistreplase Action Pathway
SMP00288Aprotinin Action Pathway
SMP00275Ardeparin Action Pathway
SMP00276Argatroban Action Pathway
SMP00277Bivalirudin Action Pathway
SMP00586Coagulation
SMP00656Dicoumarol Action Pathway
SMP00270Dicumarol Action Pathway
SMP00272Enoxaparin Action Pathway
SMP00273Fondaparinux Action Pathway
SMP00274Heparin Action Pathway
SMP00278Lepirudin Action Pathway
SMP00655Phenindione Action Pathway
SMP00271Phenprocoumon Action Pathway
SMP00285Reteplase Action Pathway
SMP00282Streptokinase Action Pathway
SMP00283Tenecteplase Action Pathway
SMP00287Tranexamic Acid Action Pathway
SMP00284Urokinase Action Pathway
SMP00268Warfarin Action Pathway
SMP00279Ximelagatran Action Pathway
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