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MGP Database

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MGP001042

Ontology/Pathway Information

Entrez Gene ID	2205
Gene Name	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Gene Symbol	FCER1A
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0005887	TAS:ProtInc	C	integral component of plasma membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0019767	IEA:Ensembl	F	IgE receptor activity
GO:0007257	IEA:Ensembl	P	activation of JUN kinase activity
GO:0038095	TAS:Reactome	P	Fc-epsilon receptor signaling pathway
GO:0045087	TAS:Reactome	P	innate immune response
GO:0019370	IEA:Ensembl	P	leukotriene biosynthetic process
GO:0050850	IEA:Ensembl	P	positive regulation of calcium-mediated signaling
GO:0045425	IEA:Ensembl	P	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0045401	IEA:Ensembl	P	positive regulation of interleukin-3 biosynthetic process
GO:0043306	IEA:Ensembl	P	positive regulation of mast cell degranulation
GO:0050731	IEA:Ensembl	P	positive regulation of peptidyl-tyrosine phosphorylation
GO:0001812	IEA:Ensembl	P	positive regulation of type I hypersensitivity
GO:0001820	IEA:Ensembl	P	serotonin secretion

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_163936	Fc epsilon receptor (FCERI) signaling
REACT_163834	FCERI mediated Ca+2 mobilization
REACT_163701	FCERI mediated MAPK activation
REACT_163994	FCERI mediated NF-kB activation
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_163769	Role of LAT2/NTAL/LAB on calcium mobilization

SMP Pathway Links

SMP ID	Description
SMP00358	Fc Epsilon Receptor I Signaling in Mast Cells