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MGP Database

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MGP001043

Ontology/Pathway Information

Entrez Gene ID	2206
Gene Name	membrane-spanning 4-domains, subfamily A, member 2
Gene Symbol	MS4A2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005768	IEA:Ensembl	C	endosome
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0032998	IEA:Ensembl	C	Fc-epsilon receptor I complex
GO:0005887	NAS:UniProtKB	C	integral component of plasma membrane
GO:0045121	IEA:Ensembl	C	membrane raft
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0019767	IEA:Ensembl	F	IgE receptor activity
GO:0007202	IEA:Ensembl	P	activation of phospholipase C activity
GO:0050663	IEA:Ensembl	P	cytokine secretion
GO:0038095	TAS:Reactome	P	Fc-epsilon receptor signaling pathway
GO:0006955	IMP:UniProtKB	P	immune response
GO:0006954	IEA:Ensembl	P	inflammatory response
GO:0045087	TAS:Reactome	P	innate immune response
GO:0043306	IEA:Ensembl	P	positive regulation of mast cell degranulation
GO:0007205	IEA:Ensembl	P	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0051279	IEA:Ensembl	P	regulation of release of sequestered calcium ion into cytosol

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_163936	Fc epsilon receptor (FCERI) signaling
REACT_163834	FCERI mediated Ca+2 mobilization
REACT_163701	FCERI mediated MAPK activation
REACT_163994	FCERI mediated NF-kB activation
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_163769	Role of LAT2/NTAL/LAB on calcium mobilization

SMP Pathway Links

SMP ID	Description
SMP00358	Fc Epsilon Receptor I Signaling in Mast Cells