MGP Database

MGP001044

Ontology/Pathway Information

Entrez Gene ID	2207
Gene Name	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Gene Symbol	FCER1G
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0032998	IEA:Ensembl	C	Fc-epsilon receptor I complex
GO:0005887	IEA:Ensembl	C	integral component of plasma membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0019767	IEA:Ensembl	F	IgE receptor activity
GO:0042590	IEA:Ensembl	P	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0019886	IEA:Ensembl	P	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0042742	IEA:Ensembl	P	defense response to bacterium
GO:0038095	TAS:Reactome	P	Fc-epsilon receptor signaling pathway
GO:0002431	IEA:Ensembl	P	Fc receptor mediated stimulatory signaling pathway
GO:0016064	IEA:Ensembl	P	immunoglobulin mediated immune response
GO:0045087	TAS:Reactome	P	innate immune response
GO:0007229	IEA:Ensembl	P	integrin-mediated signaling pathway
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0045576	IEA:Ensembl	P	mast cell activation
GO:0033026	IEA:Ensembl	P	negative regulation of mast cell apoptotic process
GO:0002283	IEA:Ensembl	P	neutrophil activation involved in immune response
GO:0030593	IEA:Ensembl	P	neutrophil chemotaxis
GO:0006911	IEA:Ensembl	P	phagocytosis, engulfment
GO:0030168	TAS:Reactome	P	platelet activation
GO:0032733	IEA:Ensembl	P	positive regulation of interleukin-10 production
GO:0032755	IEA:Ensembl	P	positive regulation of interleukin-6 production
GO:0032765	IEA:Ensembl	P	positive regulation of mast cell cytokine production
GO:0043306	IEA:Ensembl	P	positive regulation of mast cell degranulation
GO:0050766	IEA:Ensembl	P	positive regulation of phagocytosis
GO:0032760	IEA:Ensembl	P	positive regulation of tumor necrosis factor production
GO:0001812	IEA:Ensembl	P	positive regulation of type I hypersensitivity
GO:0001798	IEA:Ensembl	P	positive regulation of type IIa hypersensitivity
GO:0001805	IEA:Ensembl	P	positive regulation of type III hypersensitivity
GO:0072659	IEA:Ensembl	P	protein localization to plasma membrane
GO:0010543	IEA:Ensembl	P	regulation of platelet activation
GO:0002554	IEA:Ensembl	P	serotonin secretion by platelet

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12051	Cell surface interactions at the vascular wall
REACT_163936	Fc epsilon receptor (FCERI) signaling
REACT_163834	FCERI mediated Ca+2 mobilization
REACT_163701	FCERI mediated MAPK activation
REACT_163994	FCERI mediated NF-kB activation
REACT_1695	GPVI-mediated activation cascade
REACT_604	Hemostasis
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_798	Platelet activation, signaling and aggregation
REACT_1230	Platelet Adhesion to exposed collagen
REACT_163769	Role of LAT2/NTAL/LAB on calcium mobilization

SMP Pathway Links

SMP ID	Description
SMP00358	Fc Epsilon Receptor I Signaling in Mast Cells