MGP Database

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MGP001144

Ontology/Pathway Information

Entrez Gene ID2572
Gene Nameglutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Gene Symbol GAD2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031225 IEA:EnsemblCanchored component of membrane
GO:0030424 IEA:EnsemblCaxon
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0061202 TAS:ReactomeCclathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0005829 IEA:UniProtKB-SubCellCcytosol
GO:0000139 IEA:UniProtKB-SubCellCGolgi membrane
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042734 IEA:UniProtKB-SubCellCpresynaptic membrane
GO:0030672 IEA:EnsemblCsynaptic vesicle membrane
GO:0016595 IEA:EnsemblFglutamate binding
GO:0004351 IEA:UniProtKB-ECFglutamate decarboxylase activity
GO:0030170 IEA:InterProFpyridoxal phosphate binding
GO:0006540 TAS:ProtIncPglutamate decarboxylation to succinate
GO:0042136 IEA:UniProtKB-KWPneurotransmitter biosynthetic process
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0042493 IEA:EnsemblPresponse to drug
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_24020GABA synthesis
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_13685Neuronal System
REACT_13723Neurotransmitter Release Cycle
REACT_13477Transmission across Chemical Synapses
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