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MGP001177

Record overview

MGPD IDMGP001177
Gene ID2644
SpeciesHomo sapiens (Human)
Gene NameGTP cyclohydrolase I feedback regulator
Gene Symbol GCHFR
SynonymsP35; GFRP; HsT16933;
Alternate namesGTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulatory protein;
Chromosome15
Map Location15q15
SummaryGTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GCHFR

Proteins

GTP cyclohydrolase 1 feedback regulatory protein
Refseq ID:NP_005249
Protein GI:4885257
UniProt ID:P30047
mRNA ID:NM_005258
Length:84
RefSeq Status:
MPYLLISTQIRMEVGPTMVGDEQSDPELMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE
 
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