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MGP001197

Record overview

MGPD IDMGP001197
Gene ID2686
SpeciesHomo sapiens (Human)
Gene Namegamma-glutamyltransferase 7
Gene Symbol GGT7
SynonymsGGT4; GGTL3; GGTL5; D20S101; dJ18C9.2;
Alternate namesgamma-glutamyltransferase 7; GGT 7; gamma-glutamyltransferase 4; gamma-glutamyltransferase-like 3; gamma-glutamyltransferase-like 5; gamma-glutamyltranspeptidase 7; gamma-glutamyltranspeptidase-like 3; glutathione hydrolase 7;
Chromosome20
Map Location20q11.22
EC Number2.3.2.2
SummaryThis gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GGT7

Proteins

gamma-glutamyltransferase 7
Refseq ID:NP_821158
Protein GI:109148539
UniProt ID:Q9UJ14
mRNA ID:NM_178026
Length:662
RefSeq Status:
MAAENEASQESALGAYSPVDYMSITSFPRLPEDEPAPAAPLRGRKDEDAFLGDPDTDPDSFLKSARLQRLPSSSSEMGSQDGSPLRETRKDPFSAAAAEC
SCRQDGLTVIVTACLTFATGVTVALVMQIYFGDPQIFQQGAVVTDAARCTSLGIEVLSKQGSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRNES
HLIDFRESAPGALREETLQRSWETKPGLLVGVPGMVKGLHEAHQLYGRLPWSQVLAFAAAVAQDGFNVTHDLARALAEQLPPNMSERFRETFLPSGRPPL
PGSLLHRPDLAEVLDVLGTSGPAAFYAGGNLTLEMVAEAQHAGGVITEEDFSNYSALVEKPVCGVYRGHLVLSPPPPHTGPALISALNILEGFNLTSLVS
REQALHWVAETLKIALALASRLGDPVYDSTITESMDDMLSKVEAAYLRGHINDSQAAPAPLLPVYELDGAPTAAQVLIMGPDDFIVAMVSSLNQPFGSGL
ITPSGILLNSQMLDFSWPNRTANHSAPSLENSVQPGKRPLSFLLPTVVRPAEGLCGTYLALGANGAARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDL
QSNLLQVDSEFTEEEIEFLEARGHHVEKVDVLSWVHGSRRTNNFIIAVKDPRSPDAAGATIL
 
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