MGP Database

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MGP001197

Ontology/Pathway Information

Entrez Gene ID2686
Gene Namegamma-glutamyltransferase 7
Gene Symbol GGT7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031362 TAS:UniProtKBCanchored component of external side of plasma membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0003840 TAS:UniProtKBFgamma-glutamyltransferase activity
GO:0036374 IEA:UniProtKB-ECFglutathione hydrolase activity
GO:0006750 IEA:UniProtKB-KWPglutathione biosynthetic process
GO:0006749 TAS:UniProtKBPglutathione metabolic process
GO:0019370 ISS:UniProtKBPleukotriene biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264461Aflatoxin activation and detoxification
REACT_13433Biological oxidations
REACT_267633Defective ACY1 causes encephalopathy
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_6960Glutathione synthesis and recycling
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
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