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MGP001223

UniProt Annotations

Entry Information
Gene Nameglutamate-cysteine ligase, modifier subunit
Protein EntryGSH0_HUMAN
UniProt IDP48507
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P48507-1; Sequence=Displayed; Name=2; IsoId=P48507-2; Sequence=VSP_057008;
PathwaySulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
SimilarityBelongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily. {ECO:0000305}.
SubunitHeterodimer of a catalytic heavy chain and a regulatory light chain.
Tissue SpecificityIn all tissues examined. Highest levels in skeletal muscle.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/gclm/";
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