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MGP001270

Record overview

MGPD IDMGP001270
Gene ID2805
SpeciesHomo sapiens (Human)
Gene Nameglutamic-oxaloacetic transaminase 1, soluble
Gene Symbol GOT1
SynonymscCAT; GIG18; cAspAT; ASTQTL1;
Alternate namesaspartate aminotransferase, cytoplasmic; aspartate aminotransferase 1; aspartate transaminase 1; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; glutamate oxaloacetate transaminase 1; growth-inhibiting protein 18; transaminase A;
Chromosome10
Map Location10q24.1-q25.1
EC Number2.6.1.1
SummaryGlutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GOT1

Proteins

aspartate aminotransferase, cytoplasmic
Refseq ID:NP_002070
Protein GI:4504067
UniProt ID:P17174
mRNA ID:NM_002079
Length:413
RefSeq Status:
MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKR
VGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGID
PTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP
AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDY
VATSIHEAVTKIQ
 
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