MGP Database

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MGP001308

Ontology/Pathway Information

Entrez Gene ID2885
Gene Namegrowth factor receptor-bound protein 2
Gene Symbol GRB2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0008180 IDA:UniProtKBCCOP9 signalosome
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:HGNCCcytosol
GO:0005768 IDA:UniProtKBCendosome
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IEA:UniProtKB-SubCellCGolgi apparatus
GO:0070436 IDA:BHF-UCLCGrb2-EGFR complex
GO:0005730 IDA:HPACnucleolus
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 TAS:ReactomeCplasma membrane
GO:0012506 IEA:EnsemblCvesicle membrane
GO:0046875 IPI:UniProtKBFephrin receptor binding
GO:0005154 IPI:UniProtKBFepidermal growth factor receptor binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0043560 IPI:UniProtKBFinsulin receptor substrate binding
GO:0005168 IPI:UniProtKBFneurotrophin TRKA receptor binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0017124 IDA:UniProtKBFSH3 domain binding
GO:0005070 TAS:UniProtKBFSH3/SH2 adaptor activity
GO:0007568 IEA:EnsemblPaging
GO:0048646 IEA:EnsemblPanatomical structure formation involved in morphogenesis
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0060670 IEA:EnsemblPbranching involved in labyrinthine layer morphogenesis
GO:0007267 TAS:UniProtKBPcell-cell signaling
GO:0071479 IMP:BHF-UCLPcellular response to ionizing radiation
GO:0007173 TAS:UniProtKBPepidermal growth factor receptor signaling pathway
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0008286 IPI:UniProtKBPinsulin receptor signaling pathway
GO:0050900 TAS:ReactomePleukocyte migration
GO:0042059 TAS:ReactomePnegative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0048015 TAS:ReactomePphosphatidylinositol-mediated signaling
GO:0030168 TAS:ReactomePplatelet activation
GO:0030838 IEA:EnsemblPpositive regulation of actin filament polymerization
GO:2000379 IMP:BHF-UCLPpositive regulation of reactive oxygen species metabolic process
GO:0051291 IEA:EnsemblPprotein heterooligomerization
GO:0007265 TAS:UniProtKBPRas protein signal transduction
GO:0031623 IMP:BHF-UCLPreceptor internalization
GO:0043408 IEA:EnsemblPregulation of MAPK cascade
GO:0042770 IMP:BHF-UCLPsignal transduction in response to DNA damage
GO:0031295 TAS:ReactomePT cell costimulation
GO:0016032 IEA:UniProtKB-KWPviral process
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
SMP00391Insulin Signalling
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