MGP Database

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MGP001336

Ontology/Pathway Information

Entrez Gene ID2919
Gene Namechemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Gene Symbol CXCL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 TAS:ProtIncCextracellular space
GO:0008009 TAS:ProtIncFchemokine activity
GO:0045236 IBA:GO_CentralFCXCR chemokine receptor binding
GO:0008047 TAS:ProtIncFenzyme activator activity
GO:0005102 TAS:ProtIncFreceptor binding
GO:0030036 TAS:ProtIncPactin cytoskeleton organization
GO:0060326 TAS:GOCPcell chemotaxis
GO:0008283 TAS:ProtIncPcell proliferation
GO:0070098 IBA:GO_CentralPchemokine-mediated signaling pathway
GO:0006935 TAS:ProtIncPchemotaxis
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0006955 IBA:GO_CentralPimmune response
GO:0006954 TAS:ProtIncPinflammatory response
GO:0035556 TAS:ProtIncPintracellular signal transduction
GO:0008285 TAS:ProtIncPnegative regulation of cell proliferation
GO:0007399 TAS:ProtIncPnervous system development
GO:0043085 TAS:GOCPpositive regulation of catalytic activity
GO:0002690 IBA:GO_CentralPpositive regulation of leukocyte chemotaxis
GO:0032496 IBA:GO_CentralPresponse to lipopolysaccharide
GO:0007165 TAS:ProtIncPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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