MGP Database

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MGP001337

Ontology/Pathway Information

Entrez Gene ID2920
Gene Namechemokine (C-X-C motif) ligand 2
Gene Symbol CXCL2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 TAS:ProtIncCextracellular space
GO:0008009 TAS:ProtIncFchemokine activity
GO:0045236 IBA:GO_CentralFCXCR chemokine receptor binding
GO:0060326 TAS:GOCPcell chemotaxis
GO:0070098 IBA:GO_CentralPchemokine-mediated signaling pathway
GO:0006935 TAS:ProtIncPchemotaxis
GO:0007186 IBA:GO_CentralPG-protein coupled receptor signaling pathway
GO:0006955 IBA:GO_CentralPimmune response
GO:0006954 TAS:ProtIncPinflammatory response
GO:0002690 IBA:GO_CentralPpositive regulation of leukocyte chemotaxis
GO:0042127 IBA:GO_CentralPregulation of cell proliferation
GO:0032496 IBA:GO_CentralPresponse to lipopolysaccharide
GO:0002237 IDA:BHF-UCLPresponse to molecule of bacterial origin
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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