MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001353

Ontology/Pathway Information

Entrez Gene ID2946
Gene Nameglutathione S-transferase mu 2 (muscle)
Gene Symbol GSTM2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:BHF-UCLCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016529 IDA:BHF-UCLCsarcoplasmic reticulum
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0043295 IDA:BHF-UCLFglutathione binding
GO:0004364 IDA:UniProtKBFglutathione transferase activity
GO:0042803 IPI:BHF-UCLFprotein homodimerization activity
GO:0005102 IPI:BHF-UCLFreceptor binding
GO:0070458 IDA:BHF-UCLPcellular detoxification of nitrogen compound
GO:0071313 IDA:BHF-UCLPcellular response to caffeine
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0006749 IDA:UniProtKBPglutathione metabolic process
GO:0060315 IDA:BHF-UCLPnegative regulation of ryanodine-sensitive calcium-release channel activity
GO:0018916 IDA:BHF-UCLPnitrobenzene metabolic process
GO:0060316 IDA:BHF-UCLPpositive regulation of ryanodine-sensitive calcium-release channel activity
GO:0010881 IC:BHF-UCLPregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010880 IDA:BHF-UCLPregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0014809 IC:BHF-UCLPregulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0055119 TAS:BHF-UCLPrelaxation of cardiac muscle
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0042178 IDA:UniProtKBPxenobiotic catabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
  logo