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MGP001353

UniProt Annotations

Entry Information
Gene Nameglutathione S-transferase mu 2 (muscle)
Protein EntryGSTM2_HUMAN
UniProt IDP28161
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P28161-1; Sequence=Displayed; Name=2; IsoId=P28161-2; Sequence=VSP_045614; Note=No experimental confirmation available.;
Catalytic ActivityRX + glutathione = HX + R-S-glutathione. {ECO:0000269|PubMed:16549767}.
FunctionConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:16549767}.
SimilarityBelongs to the GST superfamily. Mu family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SimilarityContains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer. {ECO:0000269|PubMed:16549767, ECO:0000269|PubMed:19808963, ECO:0000269|PubMed:8182750}.
Tissue SpecificityMuscle.
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