MGP Database

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MGP001354

Ontology/Pathway Information

Entrez Gene ID2947
Gene Nameglutathione S-transferase mu 3 (brain)
Gene Symbol GSTM3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:BHF-UCLCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IDA:UniProtKBCnucleus
GO:0035686 IEA:EnsemblCsperm fibrous sheath
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0043295 IDA:BHF-UCLFglutathione binding
GO:0004364 IDA:UniProtKBFglutathione transferase activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0042803 IPI:BHF-UCLFprotein homodimerization activity
GO:0070458 IDA:BHF-UCLPcellular detoxification of nitrogen compound
GO:0008065 TAS:ProtIncPestablishment of blood-nerve barrier
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0006749 IDA:UniProtKBPglutathione metabolic process
GO:0018916 IDA:BHF-UCLPnitrobenzene metabolic process
GO:0043627 IEP:UniProtKBPresponse to estrogen
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0042178 IDA:BHF-UCLPxenobiotic catabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
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