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MGP001357

Record overview

MGPD IDMGP001357
Gene ID2950
SpeciesHomo sapiens (Human)
Gene Nameglutathione S-transferase pi 1
Gene Symbol GSTP1
SynonymsPI; DFN7; GST3; GSTP; FAEES3; HEL-S-22;
Alternate namesglutathione S-transferase P; GST class-pi; GSTP1-1; deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III;
Chromosome11
Map Location11q13
EC Number2.5.1.18
SummaryGlutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GSTP1

Proteins

glutathione S-transferase P
Refseq ID:NP_000843
Protein GI:4504183
UniProt ID:P09211
mRNA ID:NM_000852
Length:210
RefSeq Status:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDL
RCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYV
NLPINGNGKQ
 
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