MGP Database

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MGP001360

Ontology/Pathway Information

Entrez Gene ID2954
Gene Nameglutathione S-transferase zeta 1
Gene Symbol GSTZ1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005739 ISS:UniProtKBCmitochondrion
GO:0004602 TAS:ProtIncFglutathione peroxidase activity
GO:0004364 IDA:UniProtKBFglutathione transferase activity
GO:0016034 IDA:UniProtKBFmaleylacetoacetate isomerase activity
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0006749 IDA:UniProtKBPglutathione metabolic process
GO:0006559 TAS:ReactomePL-phenylalanine catabolic process
GO:0055114 TAS:GOCPoxidation-reduction process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006572 IEA:UniProtKB-KWPtyrosine catabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_6959Phase II conjugation
REACT_1786Phenylalanine and tyrosine catabolism
SMP Pathway Links
SMP IDDescription
SMP00169Alkaptonuria
SMP00429Disulfiram Action Pathway
SMP00498Dopamine beta-hydroxylase deficiency
SMP00190Hawkinsinuria
SMP00533Monoamine oxidase-a deficiency (MAO-A)
SMP00008Phenylalanine and Tyrosine Metabolism
SMP00206Phenylketonuria
SMP00006Tyrosine Metabolism
SMP00494Tyrosinemia, transient, of the newborn
SMP00369Tyrosinemia Type 2 (or Richner-Hanhart syndrome)
SMP00370Tyrosinemia Type 3 (TYRO3)
SMP00218Tyrosinemia Type I
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