MGP Database

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MGP001382

Ontology/Pathway Information

Entrez Gene ID2987
Gene Nameguanylate kinase 1
Gene Symbol GUK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004385 IDA:UniProtKBFguanylate kinase activity
GO:0046034 IEA:EnsemblPATP metabolic process
GO:0046060 IEA:EnsemblPdATP metabolic process
GO:0006185 IEA:EnsemblPdGDP biosynthetic process
GO:0046054 IEA:EnsemblPdGMP metabolic process
GO:0017144 TAS:ReactomePdrug metabolic process
GO:0046711 IEA:EnsemblPGDP biosynthetic process
GO:0019673 IEA:EnsemblPGDP-mannose metabolic process
GO:0034436 IEA:EnsemblPglycoprotein transport
GO:0046037 IEA:EnsemblPGMP metabolic process
GO:0015949 TAS:ReactomePnucleobase-containing small molecule interconversion
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0006163 IDA:UniProtKBPpurine nucleotide metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121388Abacavir metabolism
REACT_121189Abacavir transport and metabolism
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_21330Synthesis and interconversion of nucleotide di- and triphosphates
SMP Pathway Links
SMP IDDescription
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00430Thioguanine Action Pathway
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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