MGP Database

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MGP001445

Ontology/Pathway Information

Entrez Gene ID3109
Gene Namemajor histocompatibility complex, class II, DM beta
Gene Symbol HLA-DMB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0031902 IEA:UniProtKB-SubCellClate endosome membrane
GO:0005765 TAS:ReactomeClysosomal membrane
GO:0042613 IDA:UniProtKBCMHC class II protein complex
GO:0023026 IDA:UniProtKBFMHC class II protein complex binding
GO:0019886 IMP:UniProtKBPantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0006955 IEA:InterProPimmune response
GO:0002399 IMP:UniProtKBPMHC class II protein complex assembly
GO:0002503 IDA:UniProtKBPpeptide antigen assembly with MHC class II protein complex
GO:2001190 IMP:UniProtKBPpositive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0042102 IMP:UniProtKBPpositive regulation of T cell proliferation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_6900Immune System
REACT_121399MHC class II antigen presentation
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