MGP Database

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MGP001493

Ontology/Pathway Information

Entrez Gene ID3248
Gene Namehydroxyprostaglandin dehydrogenase 15-(NAD)
Gene Symbol HPGD
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016323 IEA:EnsemblCbasolateral plasma membrane
GO:0005829 NAS:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016404 IDA:UniProtKBF15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0003824 IDA:UniProtKBFcatalytic activity
GO:0051287 IDA:UniProtKBFNAD binding
GO:0070403 IDA:UniProtKBFNAD+ binding
GO:0004957 IDA:UniProtKBFprostaglandin E receptor activity
GO:0042803 TAS:UniProtKBFprotein homodimerization activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0019371 TAS:ReactomePcyclooxygenase pathway
GO:0097070 ISS:UniProtKBPductus arteriosus closure
GO:0007565 IDA:UniProtKBPfemale pregnancy
GO:2001300 TAS:ReactomePlipoxin metabolic process
GO:0019372 TAS:UniProtKBPlipoxygenase pathway
GO:0045786 IDA:UniProtKBPnegative regulation of cell cycle
GO:0030728 ISS:UniProtKBPovulation
GO:0007567 IDA:UniProtKBPparturition
GO:0006693 IDA:UniProtKBPprostaglandin metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0070493 ISS:UniProtKBPthrombin receptor signaling pathway
GO:0007179 IDA:UniProtKBPtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150320Synthesis of Lipoxins (LX)
REACT_150149Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
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