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MGP001537

Record overview

MGPD IDMGP001537
Gene ID3362
SpeciesHomo sapiens (Human)
Gene Name5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Gene Symbol HTR6
Synonyms5-HT6; 5-HT6R;
Alternate names5-hydroxytryptamine receptor 6; serotonin receptor 6;
Chromosome1
Map Location1p36-p35
SummaryThis gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]
OrthologsView orthologs and multiple alignments for HTR6

Proteins

5-hydroxytryptamine receptor 6
Refseq ID:NP_000862
Protein GI:4504545
UniProt ID:P50406
mRNA ID:NM_000871
Length:440
RefSeq Status:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCL
LWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLP
SGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLL
PGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
 
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