MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001565

Record overview

MGPD IDMGP001565
Gene ID3434
SpeciesHomo sapiens (Human)
Gene Nameinterferon-induced protein with tetratricopeptide repeats 1
Gene Symbol IFIT1
SynonymsC56; P56; G10P1; IFI56; ISG56; IFI-56; IFIT-1; IFNAI1; RNM561; IFI-56K;
Alternate namesinterferon-induced protein with tetratricopeptide repeats 1; interferon, alpha-inducible protein (MW 56kD); interferon-induced 56 kDa protein; interferon-inducible mRNA 561;
Chromosome10
Map Location10q23.31
SummaryThis gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
OrthologsView orthologs and multiple alignments for IFIT1

Proteins

interferon-induced protein with tetratricopeptide repeats 1 isoform 1
Refseq ID:NP_001539
Protein GI:116534937
UniProt ID:P09914
mRNA ID:NM_001548
Length:478
RefSeq Status:
MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGN
FAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKP
FSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI
QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAII
HYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
 
interferon-induced protein with tetratricopeptide repeats 1 isoform 2
Refseq ID:NP_001257856
Protein GI:400286379
UniProt ID:
mRNA ID:NM_001270927
Length:478
RefSeq Status:
MCTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGN
FAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKP
FSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI
QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAII
HYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
 
interferon-induced protein with tetratricopeptide repeats 1 isoform 3
Refseq ID:NP_001257857
Protein GI:400286381
UniProt ID:P09914
mRNA ID:NM_001270928
Length:447
RefSeq Status:
MPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNP
FRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEG
QEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFES
AVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLR
RKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
 
interferon-induced protein with tetratricopeptide repeats 1 isoform 3
Refseq ID:NP_001257859
Protein GI:400286385
UniProt ID:P09914
mRNA ID:NM_001270930
Length:447
RefSeq Status:
Protein sequence is identical to GI:400286381 (mRNA isoform)
 
interferon-induced protein with tetratricopeptide repeats 1 isoform 3
Refseq ID:NP_001257858
Protein GI:400286383
UniProt ID:P09914
mRNA ID:NM_001270929
Length:447
RefSeq Status:
Protein sequence is identical to GI:400286381 (mRNA isoform)
 
  logo