MGP Database

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MGP001565

Ontology/Pathway Information

Entrez Gene ID3434
Gene Nameinterferon-induced protein with tetratricopeptide repeats 1
Gene Symbol IFIT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0003723 IDA:UniProtKBFRNA binding
GO:0071360 IDA:BHF-UCLPcellular response to exogenous dsRNA
GO:0071357 IDA:BHF-UCLPcellular response to type I interferon
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0051607 IEA:UniProtKB-KWPdefense response to virus
GO:0019060 IDA:BHF-UCLPintracellular transport of viral protein in host cell
GO:0050689 IDA:BHF-UCLPnegative regulation of defense response to virus by host
GO:0051097 IDA:BHF-UCLPnegative regulation of helicase activity
GO:0032091 IDA:BHF-UCLPnegative regulation of protein binding
GO:0045071 IMP:UniProtKBPnegative regulation of viral genome replication
GO:0045070 IDA:BHF-UCLPpositive regulation of viral genome replication
GO:0009615 IMP:UniProtKBPresponse to virus
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115676Antiviral mechanism by IFN-stimulated genes
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25162Interferon alpha/beta signaling
REACT_25229Interferon Signaling
REACT_115831ISG15 antiviral mechanism
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