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MGP001608

Record overview

MGPD IDMGP001608
Gene ID3562
SpeciesHomo sapiens (Human)
Gene Nameinterleukin 3
Gene Symbol IL3
SynonymsIL-3; MCGF; MULTI-CSF;
Alternate namesinterleukin-3; P-cell stimulating factor; P-cell-stimulating factor; colony-stimulating factor, multiple; hematopoietic growth factor; mast cell growth factor; mast-cell growth factor; multilineage-colony-stimulating factor; multipotential colony-stimulating factor;
Chromosome5
Map Location5q31.1
SummaryThe protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for IL3

Proteins

interleukin-3 precursor
Refseq ID:NP_000579
Protein GI:28416915
UniProt ID:P08700
mRNA ID:NM_000588
Length:152
RefSeq Status:
MSRLPVLLLLQLLVRPGLQAPMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNL
LPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2160
peptide sequence: 
MSRLPVLLLLQLLVRPGLQ

mat_peptide: 20..152
product: interleukin-3
calculated_mol_wt: 15091
peptide sequence: 
APMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIK
DGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
 
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