MGP Database

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MGP001608

Ontology/Pathway Information

Entrez Gene ID3562
Gene Nameinterleukin 3
Gene Symbol IL3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 ISS:UniProtKBCextracellular space
GO:0005125 IBA:GO_CentralFcytokine activity
GO:0005135 TAS:UniProtKBFinterleukin-3 receptor binding
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0019221 IBA:GO_CentralPcytokine-mediated signaling pathway
GO:0035162 IDA:DFLATPembryonic hemopoiesis
GO:0006955 IEA:InterProPimmune response
GO:0007399 TAS:ProtIncPnervous system development
GO:0008284 ISS:UniProtKBPpositive regulation of cell proliferation
GO:0045740 IDA:BHF-UCLPpositive regulation of DNA replication
GO:0070668 IBA:GO_CentralPpositive regulation of mast cell proliferation
GO:0002763 IBA:GO_CentralPpositive regulation of myeloid leukocyte differentiation
GO:0050731 ISS:UniProtKBPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0042523 IDA:BHF-UCLPpositive regulation of tyrosine phosphorylation of Stat5 protein
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19184GPCR downstream signaling
REACT_19388G-protein beta:gamma signalling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_6900Immune System
REACT_27283Interleukin-2 signaling
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_23891Interleukin receptor SHC signaling
REACT_798Platelet activation, signaling and aggregation
REACT_14797Signaling by GPCR
REACT_22232Signaling by Interleukins
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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