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MGP001608

UniProt Annotations

Entry Information
Gene Nameinterleukin 3
Protein EntryIL3_HUMAN
UniProt IDP08700
SpeciesHuman
Comments
Comment typeDescription
FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
FunctionThis CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
InteractionP32927:CSF2RB; NbExp=1; IntAct=EBI-1811718, EBI-1809771;
SimilarityBelongs to the IL-3 family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitMonomer.
Tissue SpecificityActivated T-cells, mast cells, natural killer cells.
Web ResourceName=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/IL3ID60.html";
Web ResourceName=SeattleSNPs; URL="http://pga.gs.washington.edu/data/il3/";
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