MGP Database

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MGP001622

Ontology/Pathway Information

Entrez Gene ID3606
Gene Nameinterleukin 18
Gene Symbol IL18
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 TAS:UniProtKBCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005125 TAS:UniProtKBFcytokine activity
GO:0001525 IDA:UniProtKBPangiogenesis
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0071407 IDA:UniProtKBPcellular response to organic cyclic compound
GO:0042033 TAS:UniProtKBPchemokine biosynthetic process
GO:0042253 TAS:UniProtKBPgranulocyte macrophage colony-stimulating factor biosynthetic process
GO:0006955 TAS:ProtIncPimmune response
GO:0006954 IDA:UniProtKBPinflammatory response
GO:0042095 TAS:UniProtKBPinterferon-gamma biosynthetic process
GO:0042231 TAS:UniProtKBPinterleukin-13 biosynthetic process
GO:0042094 TAS:UniProtKBPinterleukin-2 biosynthetic process
GO:0031663 IDA:UniProtKBPlipopolysaccharide-mediated signaling pathway
GO:0000165 IMP:UniProtKBPMAPK cascade
GO:0030101 IEA:EnsemblPnatural killer cell activation
GO:0042104 IDA:UniProtKBPpositive regulation of activated T cell proliferation
GO:0010628 IEA:EnsemblPpositive regulation of gene expression
GO:0032725 IDA:BHF-UCLPpositive regulation of granulocyte macrophage colony-stimulating factor production
GO:0050729 IC:BHF-UCLPpositive regulation of inflammatory response
GO:0032729 IDA:BHF-UCLPpositive regulation of interferon-gamma production
GO:0032740 IDA:BHF-UCLPpositive regulation of interleukin-17 production
GO:0032819 IDA:BHF-UCLPpositive regulation of natural killer cell proliferation
GO:0042346 IEA:EnsemblPpositive regulation of NF-kappaB import into nucleus
GO:0051142 IDA:BHF-UCLPpositive regulation of NK T cell proliferation
GO:0034105 IC:BHF-UCLPpositive regulation of tissue remodeling
GO:0030155 IDA:UniProtKBPregulation of cell adhesion
GO:0030431 ISS:UniProtKBPsleep
GO:0042088 IDA:UniProtKBPT-helper 1 type immune response
GO:0042092 TAS:UniProtKBPtype 2 immune response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_23950Interleukin-1 processing
REACT_22232Signaling by Interleukins
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