MGP Database

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MGP001892

Ontology/Pathway Information

Entrez Gene ID4190
Gene Namemalate dehydrogenase 1, NAD (soluble)
Gene Symbol MDH1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:HPACcentrosome
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0047860 IEA:UniProtKB-ECFdiiodophenylpyruvate reductase activity
GO:0030060 TAS:ReactomeFL-malate dehydrogenase activity
GO:0004470 TAS:ProtIncFmalic enzyme activity
GO:0051287 IEA:EnsemblFNAD binding
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0044262 IEA:InterProPcellular carbohydrate metabolic process
GO:0006094 TAS:ReactomePgluconeogenesis
GO:0006006 TAS:ReactomePglucose metabolic process
GO:0006108 IEA:InterProPmalate metabolic process
GO:0006734 IEA:EnsemblPNADH metabolic process
GO:0006107 IEA:EnsemblPoxaloacetate metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006099 IEA:UniProtKB-KWPtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_1520Gluconeogenesis
REACT_723Glucose metabolism
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
SMP Pathway Links
SMP IDDescription
SMP00196Leigh Syndrome
SMP00558Primary hyperoxaluria II, PH2
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
SMP00466Transfer of Acetyl Groups into Mitochondria
SMP00654Warburg Effect
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