MGP Database

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MGP001893

Ontology/Pathway Information

Entrez Gene ID4191
Gene Namemalate dehydrogenase 2, NAD (mitochondrial)
Gene Symbol MDH2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0030060 IDA:UniProtKBFL-malate dehydrogenase activity
GO:0046554 IEA:EnsemblFmalate dehydrogenase (NADP+) activity
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0044262 IEA:InterProPcellular carbohydrate metabolic process
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006094 TAS:ReactomePgluconeogenesis
GO:0006006 TAS:ReactomePglucose metabolic process
GO:0006475 IDA:UniProtKBPinternal protein amino acid acetylation
GO:0006108 IDA:UniProtKBPmalate metabolic process
GO:0006734 IEA:EnsemblPNADH metabolic process
GO:0006107 IEA:EnsemblPoxaloacetate metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1785Citric acid cycle (TCA cycle)
REACT_116125Disease
REACT_1520Gluconeogenesis
REACT_723Glucose metabolism
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00562Fructose-1,6-diphosphatase deficiency
SMP00547Fumarase deficiency
SMP00128Gluconeogenesis
SMP00581Glycogenosis, Type IA. Von gierke disease
SMP00573Glycogenosis, Type IB
SMP00574Glycogenosis, Type IC
SMP00374Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00129Malate-Aspartate Shuttle
SMP00548Mitochondrial complex II deficiency
SMP00560Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00563Triosephosphate isomerase
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