MGP Database

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MGP001921

Ontology/Pathway Information

Entrez Gene ID4258
Gene Namemicrosomal glutathione S-transferase 2
Gene Symbol MGST2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0043231 IDA:UniProtKBCintracellular membrane-bounded organelle
GO:0005635 IBA:GO_CentralCnuclear envelope
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0008047 IEA:InterProFenzyme activator activity
GO:0004602 IBA:GO_CentralFglutathione peroxidase activity
GO:0004364 IDA:UniProtKBFglutathione transferase activity
GO:0004464 IDA:UniProtKBFleukotriene-C4 synthase activity
GO:0006750 IDA:UniProtKBPglutathione biosynthetic process
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0019370 IDA:UniProtKBPleukotriene biosynthetic process
GO:0055114 IBA:GOCPoxidation-reduction process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264461Aflatoxin activation and detoxification
REACT_13433Biological oxidations
REACT_267633Defective ACY1 causes encephalopathy
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
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