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MGP001926

Record overview

MGPD IDMGP001926
Gene ID4282
SpeciesHomo sapiens (Human)
Gene Namemacrophage migration inhibitory factor (glycosylation-inhibiting factor)
Gene Symbol MIF
SynonymsGIF; GLIF; MMIF;
Alternate namesmacrophage migration inhibitory factor; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase;
Chromosome22
Map Location22q11.23
EC Number5.3.2.1
SummaryThis gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MIF

Proteins

macrophage migration inhibitory factor
Refseq ID:NP_002406
Protein GI:4505185
UniProt ID:P14174
mRNA ID:NM_002415
Length:115
RefSeq Status:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYY
DMNAANVGWNNSTFA
 
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