MGP Database

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MGP001926

Ontology/Pathway Information

Entrez Gene ID4282
Gene Namemacrophage migration inhibitory factor (glycosylation-inhibiting factor)
Gene Symbol MIF
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0005737 IDA:HPACcytoplasm
GO:0005576 IDA:UniProtKBCextracellular region
GO:0005615 IEA:UniProtKB-KWCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005654 IDA:HPACnucleoplasm
GO:0031982 IDA:UniProtKBCvesicle
GO:0042056 IDA:BHF-UCLFchemoattractant activity
GO:0005125 IDA:UniProtKBFcytokine activity
GO:0005126 IPI:BHF-UCLFcytokine receptor binding
GO:0004167 IDA:UniProtKBFdopachrome isomerase activity
GO:0050178 IDA:MGIFphenylpyruvate tautomerase activity
GO:0005102 IPI:BHF-UCLFreceptor binding
GO:0019752 IDA:BHF-UCLPcarboxylic acid metabolic process
GO:0007569 IEA:EnsemblPcell aging
GO:0008283 IDA:UniProtKBPcell proliferation
GO:0007166 IDA:UniProtKBPcell surface receptor signaling pathway
GO:0030330 IEA:EnsemblPDNA damage response, signal transduction by p53 class mediator
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 IEA:UniProtKB-KWPinnate immune response
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0090344 IDA:BHF-UCLPnegative regulation of cell aging
GO:0071157 IDA:BHF-UCLPnegative regulation of cell cycle arrest
GO:0032269 IEA:EnsemblPnegative regulation of cellular protein metabolic process
GO:0043518 IDA:BHF-UCLPnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0010629 IDA:BHF-UCLPnegative regulation of gene expression
GO:1902166 IDA:BHF-UCLPnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0002906 IEA:EnsemblPnegative regulation of mature B cell apoptotic process
GO:0033033 IEA:EnsemblPnegative regulation of myeloid cell apoptotic process
GO:0050918 IDA:GOCPpositive chemotaxis
GO:0090238 IEA:EnsemblPpositive regulation of arachidonic acid secretion
GO:0030890 IDA:BHF-UCLPpositive regulation of B cell proliferation
GO:2000343 IEA:EnsemblPpositive regulation of chemokine (C-X-C motif) ligand 2 production
GO:0050715 IDA:BHF-UCLPpositive regulation of cytokine secretion
GO:0070374 IDA:BHF-UCLPpositive regulation of ERK1 and ERK2 cascade
GO:0048146 IDA:BHF-UCLPpositive regulation of fibroblast proliferation
GO:0031666 IEA:EnsemblPpositive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043406 IEA:EnsemblPpositive regulation of MAP kinase activity
GO:0061081 IEA:EnsemblPpositive regulation of myeloid leukocyte cytokine production involved in immune response
GO:0033138 IDA:BHF-UCLPpositive regulation of peptidyl-serine phosphorylation
GO:0050731 IDA:BHF-UCLPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0042327 IDA:BHF-UCLPpositive regulation of phosphorylation
GO:0061078 IEA:EnsemblPpositive regulation of prostaglandin secretion involved in immune response
GO:0010739 IDA:BHF-UCLPpositive regulation of protein kinase A signaling
GO:0001516 IDA:UniProtKBPprostaglandin biosynthetic process
GO:0070207 IPI:UniProtKBPprotein homotrimerization
GO:0043030 NAS:UniProtKBPregulation of macrophage activation
SMP Pathway Links
SMP IDDescription
SMP00169Alkaptonuria
SMP00429Disulfiram Action Pathway
SMP00498Dopamine beta-hydroxylase deficiency
SMP00190Hawkinsinuria
SMP00533Monoamine oxidase-a deficiency (MAO-A)
SMP00006Tyrosine Metabolism
SMP00494Tyrosinemia, transient, of the newborn
SMP00218Tyrosinemia Type I
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