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MGP001988

Record overview

MGPD IDMGP001988
Gene ID4597
SpeciesHomo sapiens (Human)
Gene Namemevalonate (diphospho) decarboxylase
Gene Symbol MVD
SynonymsMPD; MDDase; FP17780;
Alternate namesdiphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase;
Chromosome16
Map Location16q24.3
EC Number4.1.1.33
SummaryThe enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MVD

Proteins

diphosphomevalonate decarboxylase
Refseq ID:NP_002452
Protein GI:4505289
UniProt ID:P53602
mRNA ID:NM_002461
Length:400
RefSeq Status:
MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGD
PLPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLIL
VVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV
AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA
 
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