MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002037

Ontology/Pathway Information

Entrez Gene ID4690
Gene NameNCK adaptor protein 1
Gene Symbol NCK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0005737 NAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005783 IDA:ParkinsonsUK-UCLCendoplasmic reticulum
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0000164 IDA:ParkinsonsUK-UCLCprotein phosphatase type 1 complex
GO:0012506 IEA:EnsemblCvesicle membrane
GO:0008093 NAS:UniProtKBFcytoskeletal adaptor activity
GO:0071074 IDA:ParkinsonsUK-UCLFeukaryotic initiation factor eIF2 binding
GO:0030674 IC:ParkinsonsUK-UCLFprotein binding, bridging
GO:0004860 IDA:UniProtKBFprotein kinase inhibitor activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0030159 NAS:UniProtKBFreceptor signaling complex scaffold activity
GO:0030971 IPI:UniProtKBFreceptor tyrosine kinase binding
GO:0005070 NAS:ParkinsonsUK-UCLFSH3/SH2 adaptor activity
GO:0007015 IEA:EnsemblPactin filament organization
GO:0007411 TAS:ReactomePaxon guidance
GO:0016477 IEA:EnsemblPcell migration
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS:ReactomePinnate immune response
GO:0030032 IEA:EnsemblPlamellipodium assembly
GO:0060548 IDA:UniProtKBPnegative regulation of cell death
GO:1900102 IDA:ParkinsonsUK-UCLPnegative regulation of endoplasmic reticulum unfolded protein response
GO:0033137 IDA:ParkinsonsUK-UCLPnegative regulation of peptidyl-serine phosphorylation
GO:0006469 IDA:GOCPnegative regulation of protein kinase activity
GO:1990441 IDA:ParkinsonsUK-UCLPnegative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:0070262 IDA:ParkinsonsUK-UCLPpeptidyl-serine dephosphorylation
GO:0030838 IMP:UniProtKBPpositive regulation of actin filament polymerization
GO:1902237 IDA:ParkinsonsUK-UCLPpositive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0042102 IMP:UniProtKBPpositive regulation of T cell proliferation
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0032056 IDA:ParkinsonsUK-UCLPpositive regulation of translation in response to stress
GO:0060734 IDA:ParkinsonsUK-UCLPregulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress
GO:0051707 IEA:EnsemblPresponse to other organism
GO:0007172 NAS:UniProtKBPsignal complex assembly
GO:0042110 IMP:UniProtKBPT cell activation
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_19226Activation of Rac
REACT_75774Adaptive Immune System
REACT_118700Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
REACT_18266Axon guidance
REACT_111155Cell-Cell communication
REACT_22351DCC mediated attractive signaling
REACT_111045Developmental Biology
REACT_17025Downstream signal transduction
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_12623Generation of second messenger molecules
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_23832Nephrin interactions
REACT_22237Netrin-1 signaling
REACT_160086Regulation of actin dynamics for phagocytic cup formation
REACT_16888Signaling by PDGF
REACT_19351Signaling by Robo receptor
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_12526TCR signaling
REACT_264464VEGFA-VEGFR2 Pathway
  logo