MGP Database

MGP002105

Record overview

MGPD IDMGP002105
Gene ID4831
SpeciesHomo sapiens (Human)
Gene NameNME/NM23 nucleoside diphosphate kinase 2
Gene Symbol NME2
SynonymsPUF; NDKB; NDPKB; NM23B; NDPK-B; NM23-H2;
Alternate namesnucleoside diphosphate kinase B; HEL-S-155an; NDP kinase B; c-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; histidine protein kinase NDKB; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; nucleotide diphosphate kinase B;
Chromosome17
Map Location17q21.3
EC Number2.7.4.6
SummaryNucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]
OrthologsView orthologs and multiple alignments for NME2

Proteins

nucleoside diphosphate kinase B isoform a
Refseq ID:NP_002503
Protein GI:4505409
UniProt ID:P22392
mRNA ID:NM_002512
Length:152
RefSeq Status:
MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSK
PGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
 
nucleoside diphosphate kinase B isoform a
Refseq ID:NP_001018149
Protein GI:66392227
UniProt ID:P22392
mRNA ID:NM_001018139
Length:152
RefSeq Status:
Protein sequence is identical to GI:4505409 (mRNA isoform)
 
nucleoside diphosphate kinase B isoform a
Refseq ID:NP_001018148
Protein GI:66392205
UniProt ID:P22392
mRNA ID:NM_001018138
Length:152
RefSeq Status:
Protein sequence is identical to GI:4505409 (mRNA isoform)
 
nucleoside diphosphate kinase B isoform a
Refseq ID:NP_001018147
Protein GI:66392192
UniProt ID:P22392
mRNA ID:NM_001018137
Length:152
RefSeq Status:
Protein sequence is identical to GI:4505409 (mRNA isoform)
 
nucleoside diphosphate kinase B isoform b
Refseq ID:NP_001185611
Protein GI:310923127
UniProt ID:F6XY72
mRNA ID:NM_001198682
Length:82
RefSeq Status:
MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMEHHSWQ
 
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