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MGP002259

Record overview

MGPD IDMGP002259
Gene ID5217
SpeciesHomo sapiens (Human)
Gene Nameprofilin 2
Gene Symbol PFN2
SynonymsPFL; D3S1319E;
Alternate namesprofilin-2; profilin II;
Chromosome3
Map Location3q25.1
SummaryThe protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PFN2

Proteins

profilin-2 isoform a
Refseq ID:NP_444252
Protein GI:16753215
UniProt ID:P35080
mRNA ID:NM_053024
Length:140
RefSeq Status:
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYN
VAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
 
profilin-2 isoform b
Refseq ID:NP_002619
Protein GI:4505751
UniProt ID:P35080
mRNA ID:NM_002628
Length:140
RefSeq Status:
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYN
VAVGRAGRALVIVMGKEGVHGGTLNKKAYELALYLRRSDV
 
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